Biomarker testing for breast cancer
Decision support for or against chemotherapy
Early-stage breast cancer tumors can often be completely removed surgically. However, cancer cells may remain in the body and grow again at a later stage. For this reason, doctors often recommend preventive chemotherapy in addition to anti-hormone therapy, although this is not always necessary due to its lengthy and severe side effects. This is where gene expression tests come in. They determine the individual risk of recurrence and can help breast cancer patients in the early stages of the tumor to choose the right therapy.
Gene expression testing for breast cancer
The term “gene expression” literally means “the expression of a gene.” Gene expression tests reveal certain characteristics of a tumor that can provide information about the individual risk of recurrence. Gene expression tests are used to examine whether certain genes are particularly active in the cancer cells. This allows patients to decide together with their doctor whether chemotherapy is the right choice.
The gene expression test used in statutory health insurance is the Oncotype DX® test. To date, this is the only test that has been proven to ensure optimal therapy and predict the benefits of chemotherapy.
When is the biomarker test considered?
In general, gene expression analysis is possible for patients in the early stages of breast cancer or specific gynecological tumors. The use of Oncotype DX® requires that no clear recommendation for or against chemotherapy can be made based on clinical and pathological criteria alone.
You can find more information in the patient information sheet:
What costs does SBK cover?
SBK covers the costs of the Oncotype DX® biomarker test. This is billed directly via the SBK healthcare card.
How to get the biomarker test for breast cancer
The test requires a tissue sample from the tumor, which is usually available after breast surgery. The analysis of the tumor tissue is arranged by the treating physician's office or clinic if the above criteria are met. The test results provide additional information that can serve as a supporting recommendation for the patient and the doctor when deciding on further treatment. The decision for or against chemotherapy always depends on other factors, such as the patient's age, general state of health, or personal situation.
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